KH-259 (compound 1) is a potent, selective and CNS-penetrant HDAC6 inhibitor, with an IC50 of 0.26 µM. KH-259 has antidepressant effects in mice through the inhibition of HDAC6 in the brain. KH-259 can be used for neurodegenerative diseases research[1].
Molecular Weight:
339.43
CAS Number:
[3023019-93-1]
Formula:
C20H25N3O2
Target:
HDAC
Application Notes:
Reference compound
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