PARP1/BRD4-IN-2 is a potent and selective PARP1 and BRD4 inhibitor with IC50 values of 197 nM and 238 nM, respectively. PARP1/BRD4-IN-2 inhibits DNA damage repair, arrests G0/G1 transition and induces apoptosis. PARP1/BRD4-IN-2 has anti-tumor activity in
Molecular Weight:
440.45
Formula:
C25H20N4O4
Target:
Apoptosis,Epigenetic Reader Domain,PARP
Application Notes:
Reference compound
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