PI3Kalpha-IN-9 (compound 27) is a selective, long-acting and oral active PI3Kalpha inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kalpha, PI3Kgamma, PI3Kdelta and PI3Kbeta, respectively. PI3Kalpha-IN-9 has antiproliferative activity and induces apoptosis. PI3Kalpha-IN-9
Molecular Weight:
383.40
Purity:
99.17
CAS Number:
[2715287-67-3]
Formula:
C18H21N7O3
Target:
Apoptosis,PI3K
Application Notes:
Reference compound
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