NIC-0102 is an orally active proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammatory vesicle activation. NIC-0102 shows potent anti-inflammatory effects in a model of dextran sulfate sodium (DSS)-induced ulcerative colitis. NIC-01
Molecular Weight:
418.24
Purity:
98.72
CAS Number:
[2806031-94-5]
Formula:
C21H25BF2N2O4
Target:
NOD-like Receptor (NLR),Proteasome
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted