JAK-IN-23 is an orally active double inhibitor of JAK/STAT and NF-kappaB. JAK-IN-23 can inhibit JAK1/2/3 with IC50 values of 8.9 nM, 15 nM and 46.2 nM, respectively. JAK-IN-23 has potent inhibitory activities against interferon-stimulated genes (ISG) and NF-
Molecular Weight:
441.35
Purity:
98.90
CAS Number:
[3031837-35-8]
Formula:
C23H22Cl2N4O
Target:
JAK,NF-kappaB,STAT,STING
Application Notes:
Reference compound
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