KU-177 is a potent inhibitor of Hsp90 ATPase homologue 1 (Aha1), ablates Aha1-driven enhancement of Hsp90-dependent tau aggregation. KU-177 also disrupts Aha1/Hsp90 interactions (IC50=4.08 µM) without inhibition of Hsp90s ATPase activity. KU-177 can be
Molecular Weight:
489.47
CAS Number:
[1160952-43-1]
Formula:
C27H23NO8
Target:
HSP
Application Notes:
Reference compound
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