NHE3-IN-3 (Compound 1) is a Na+/H+ exchanger isoform 3 (NHE3) inhibitor with pIC50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague-Dawley rats[1].
Molecular Weight:
371.28
CAS Number:
[543734-50-5]
Formula:
C16H16Cl2N2O2S
Target:
Sodium Channel
Application Notes:
Reference compound
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