IRAK4-IN-22 (compound 18) is an orally active, potent and selective IRAK4 inhibitor with IC50 values of 3 and 17 nM for IRAK4 and TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production (IC50=0.10 µM) and can be used in studies of autoimmun
Molecular Weight:
513.57
Purity:
98.20
CAS Number:
[2170694-05-8]
Formula:
C28H28FN7O2
Target:
IRAK
Application Notes:
Reference compound
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