RET-IN-19 (compound 59) is a potent RET inhibitor, with IC50 values of 6.8 and 13.51 nM against RET-wt and RET V804M, respectively. RET-IN-19 shows anticancer activity. RET-IN-19 can be used for non-small cell lung cancer (NSCLC) research[1].
Molecular Weight:
544.62
CAS Number:
[2484919-71-1]
Formula:
C28H28N6O4S
Target:
Aurora Kinase,c-Fms,EGFR,MAP4K,RET
Application Notes:
Reference compound
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