TK-129 is an orally active, low-toxicity, potent KDM5B inhibitor (with high affinity, IC50=44 nM). TK-129 exerts cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 reduces ang II-induced activation of cardi
Molecular Weight:
305.38
Purity:
98
CAS Number:
[3031476-73-7]
Formula:
C15H23N5O2
Target:
Histone Demethylase
Application Notes:
Reference compound
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