JS25 is a selective and covalent inhibitor of BTK that inactivates BTK with an IC50 value of 5.8 nM by chelating Tyr551. JS25 inhibits cancer cells proliferation, pronounces cell death, and promotes murine xenograft model of Burkitts lymphoma. JS25 effe
Molecular Weight:
524.59
Purity:
98.37
CAS Number:
[2411771-95-2]
Formula:
C29H24N4O4S
Target:
Btk
Application Notes:
Reference compound
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