Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising appr
Molecular Weight:
489.64
Purity:
98.55
CAS Number:
[1290543-63-3]
Formula:
C27H41F2N5O
Target:
Apoptosis,gamma-secretase
Application Notes:
Reference compound
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