Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib synchronously activates FoxO3a and NF-kappaB through inhibition of Akt leading to p53-i
Molecular Weight:
458
Purity:
99.88
CAS Number:
[1001264-89-6]
Formula:
C24H32ClN5O2
Target:
Akt,Apoptosis,Organoid
Application Notes:
Reference compound
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