SJ988497 is a PROTAC JAK2 degrader. SJ988497 potently inhibits CRLF2-rearranged (CRLF2r) cell proliferation and degrades the CRBN neosubstrate GSPT1. SJ988497 consists of a Ruxolitinib (HY-50856) derivative, linker, and CRBN ligand Pomalidomide. SJ988497
Molecular Weight:
688.74
Purity:
98.05
CAS Number:
[2595365-41-4]
Formula:
C36H36N10O5
Target:
JAK,PROTACs
Application Notes:
Reference compound
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