Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 µM, 0.31 µM, 0.20 µM, and 0.62 µM, respectively. Sabutoclax increases Bax, Bim, PUMA and survivin expression[1][2].
Molecular Weight:
700.78
Purity:
99.8
CAS Number:
[1228108-65-3]
Formula:
C42H40N2O8
Target:
Bcl-2 Family
Application Notes:
Reference compound
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