JNK3 inhibitor-4 is a potent inhibitor of JNK3 (IC50=1.0 nM) based on 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile. JNK3 inhibitor-4 shows excellent selectivity over other protein kinases including isoforms JNK1 (IC50=143.9 nM) and JNK2 (IC50=298.
Molecular Weight:
477.56
Purity:
99.37
CAS Number:
[2409109-65-3]
Formula:
C28H27N7O
Target:
JNK
Application Notes:
Reference compound
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