TD1092 is a pan-IAP degrader, degrades cIAP1, cIAP2, and XIAP. TD1092 activates Caspase 3/7, and promotes cancer cells apoptosis via IAP degradation. TD1092 inhibits TNFalpha mediated NF-kappaB pathway and reduces the phosphorylation of IKK, IkBalpha, p65, and p38.
Molecular Weight:
987.19
Purity:
99.49
Formula:
C55H70N8O9
Target:
Caspase,IAP,PROTACs
Application Notes:
Reference compound
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