ZC0109 is a dual inhibitor of IDO1 and thioredoxin reductase 1 (TrxR1) with IC50s of 50 nM and 3.0 µM, respectively. ZC0109 induces ROS accumulation and cell cycle arrest at G1/S phase, thus leads to cancer cells apoptosis[1].
Molecular Weight:
591.41
Purity:
99.32
Formula:
C22H20BrFN8O4S
Target:
Apoptosis,Indoleamine 2,3-Dioxygenase (IDO)
Application Notes:
Reference compound
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