RET-IN-20 is a potent RET inhibitor with an IC50 value of 13.7 nM. RET-IN-20 decreases the expression of p-Ret, p-Shc protein. RET-IN-20 induces apoptosis. RET-IN-20 shows antiproliferative and anti-tumor activity[1].
Molecular Weight:
584.64
Formula:
C32H33FN6O4
Target:
Apoptosis,RET
Application Notes:
Reference compound
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