HEC96719 is a selective and orally active tricyclic farnesoid X receptor (FXR) agonist with EC50 values of 1.37 and 1.55 nM by time-resolved fluorescence energy transfer (TR-FRET) and luciferase reporter assays, respectively. HEC96719 significantly improves non-alcoholic steatohepatitis (NASH) and liver fibrosis with favorable tissue distribution in liver and intestine. HEC96719 can be used for the research of non-alcoholic steatohepatitis[1].
Molecular Weight:
549.40
Purity:
98.01
CAS Number:
[2181834-03-5]
Formula:
C29H22Cl2N2O5
Target:
FXR
Application Notes:
MCE Product type: Reference compound
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