RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 µM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells[1].
Molecular Weight:
361.61
Purity:
99.83
CAS Number:
[415713-60-9]
Formula:
C14H11Cl3N2O3
Target:
RAD51
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
