Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntingtons disease[1][2].
Molecular Weight:
248.71
Purity:
99.89
CAS Number:
[49843-98-3]
Formula:
C13H13ClN2O
Target:
Sirtuin
Application Notes:
Reference compound
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