(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 26030 nM, 17010 nM, and 48040 nM, respectively.
Molecular Weight:
578.61
Purity:
98.93
CAS Number:
[866541-93-7]
Formula:
C32H34O10
Target:
Autophagy,Bcl-2 Family
Application Notes:
Reference compound
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