PF-07247685 is a BCKDC kinase (BDK) inhibitor (EC50=2.2 nM). PF-07247685 stabilizes the interaction between BDK and BCKDH core subunit E2 and prevents phosphorylation of E1. While BDK mediates branched-chain ketoacid dehydrogenase (BCKDH) phosphorylation
Molecular Weight:
380.46
Purity:
99.57
Formula:
C21H20N2O3S
Target:
Endogenous Metabolite
Application Notes:
Reference compound
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