VEGFR-2-IN-36 (compound 15) is a VEGFR-2 inhibitor (IC50: 0.067 µM) and inducer of apoptosis with anticancer activity. VEGFR-2-IN-36 upregulates BAX levels and downregulates Bcl-2 levels. VEGFR-2-IN-36 is toxic to cancer cells, MCF-7 (IC50=0.42 µM) and H
Molecular Weight:
489.48
Formula:
C24H23N7O5
Target:
Apoptosis,Bcl-2 Family,VEGFR
Application Notes:
Reference compound
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