SWTX-143 is a novel covalent YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity[1].
Molecular Weight:
361.36
Purity:
99.81
CAS Number:
[2766575-48-6]
Formula:
C19H18F3N3O
Target:
YAP
Application Notes:
Reference compound
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