JAK3-IN-14 (compound 1) is a potent JAK3 inhibitor, with IC50 values of 38 and 600 nM for JAK3 and JAK2, respectively. JAK3-IN-14 shows inhibitory of IL-4 and IL-3 induced TF-1 cell proliferation, with IC50 values of 600 and 500 nM, respectively[1].
Molecular Weight:
287.32
Purity:
99.32
CAS Number:
[454234-24-3]
Formula:
C18H13N3O
Target:
JAK
Application Notes:
Reference compound
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