CRM1-IN-2 (Compound KL2) is a noncovalent CRM1 inhibitor. CRM1-IN-2 localizes CRM1 in the nuclear periphery, depletes nuclear CRM1, and inhibits CRM1-mediated nuclear export. CRM1-IN-2 inhibits growth of colorectal cancer cells, and induces apoptosis[1].
Molecular Weight:
504.70
Formula:
C29H48N2O5
Target:
Apoptosis,CRM1
Application Notes:
Reference compound
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