PIK5-12d is a PROTAC PIKfyve degrader (DC50: 1.48 nM). PIK5-12d induces massive cytoplasmic vacuolization and blocks autophagic flux in multiple prostate cancer cells. PIK5-12d inhibits prostate cancer cell proliferation. PIK5-12d has anti-tumor activity
Molecular Weight:
973.19
Purity:
99.90
Formula:
C52H64N10O7S
Target:
Autophagy,PIKfyve,PROTACs
Application Notes:
Reference compound
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