LP23 is a non-arylmethylamine PD-1/PD-L1 inhibitor (IC50: 16.7 nM) with anti-tumor activity. LP23 restores immune cell function in HepG2/Jurkat T cells and promotes HepG2 cell death. LP23 is active in vivo in the B16-F10 tumor model (TGI=88.6% at 30 mg/k
Molecular Weight:
505.59
CAS Number:
[3008239-25-3]
Formula:
C27H27N3O5S
Target:
PD-1/PD-L1
Application Notes:
Reference compound
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