VHL-IN-1 (compound 30) is a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor (dissociation constant Kd=37 nM) that stabilizes and induces HIF-1alpha transcriptional activity. VHL-IN-1 has potential as a HIF-1alpha stabilizer and degrader of proteolytically
Molecular Weight:
544.68
Purity:
99.78
CAS Number:
[3033117-53-9]
Formula:
C28H37FN4O4S
Target:
HIF/HIF Prolyl-Hydroxylase,Ligands for E3 Ligase
Application Notes:
Reference compound
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