PDK-IN-2 (Compound 1F) is a PDK inhibitor (IC50: 68 nM). PDK-IN-2 inhibits the cellular expression of PDK1 and PDK4. PDK-IN-2 enhances mitochondrial bioenergetics, attenuates glycolytic phenotypes, and induces cell apoptosis in the mitochondrial pathway.
Molecular Weight:
497.33
CAS Number:
[3032446-61-7]
Formula:
C17H23AsCl2N2O2S2
Target:
Mitochondrial Metabolism,PDHK
Application Notes:
Reference compound
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