KPT-185 is an orally bioavailable and selective inhibitor of CRM1 and displays potent antiproliferative properties at submicromolar concentrations (IC50=100-500 nM), induces apoptosis, cell-cycle arrest, and myeloid differentiation in AML cell lines and
Molecular Weight:
355.31
Purity:
98.21
CAS Number:
[1333151-73-7]
Formula:
C16H16F3N3O3
Target:
CRM1
Application Notes:
Reference compound
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