LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 µM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice[1].
Molecular Weight:
537.57
Purity:
98.05
Formula:
C30H27N5O5
Target:
STING
Application Notes:
Reference compound
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