DHFR-IN-8 (compound 6r) is a dihydrofolate reductase (DHFR) inhibitor that affects purine and thymidylate biosynthesis in cell proliferation and growth. DHFR-IN-8 inhibits methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 (IC50=15.6 ng/mL) in
Molecular Weight:
346.41
CAS Number:
[3032441-09-8]
Formula:
C18H14N6S
Target:
Bacterial,Dihydrofolate reductase (DHFR)
Application Notes:
Reference compound
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