SC144 is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream
Molecular Weight:
322.30
Purity:
98.50
CAS Number:
[895158-95-9]
Formula:
C16H11FN6O
Target:
Apoptosis,Interleukin Related
Application Notes:
Reference compound
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