SC144 hydrochloride is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits
Molecular Weight:
358.76
Purity:
99.34
CAS Number:
[917497-70-2]
Formula:
C16H12ClFN6O
Target:
Apoptosis,Interleukin Related
Application Notes:
Reference compound
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