PARP1-IN-16 (compound 12a) is a potent PARP1 inhibitor, with an IC50 of 1.89 nM. PARP1-IN-16 can arrest the cell cycle in S phase and induce apoptosis in HCT-116 cells[1].
Molecular Weight:
711.74
Formula:
C40H34FN7O5
Target:
Apoptosis,PARP
Application Notes:
Reference compound
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