Aurora A inhibitor 3 (Compound 5h) inhibits Aurora-A kinase with an IC50 value of 0.78 µM. Aurora A inhibitor 3 is cytotoxic, with GI50 values of 0.12 µM and 0.63 µM for MCF-7 and MDA-MB-231 cells, respectively[1].
Molecular Weight:
409.89
Formula:
C22H21ClFN5
Target:
Aurora Kinase
Application Notes:
Reference compound
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