SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma[1].
Molecular Weight:
505.64
CAS Number:
[2136270-56-7]
Formula:
C26H31N7O2S
Target:
Akt,E1/E2/E3 Enzyme,ERK
Application Notes:
Reference compound
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