HTH-02-006 is a NUAK2 inhibitor (IC50=126 nM). HTH-02-006 reduces levels of phosphorylated MYPT1 in HuCCT-1 cells. HTH-02-006 inhibits YAP-driven cell proliferation, hepatomegaly and tumorigenesis. HTH-02-006 also has antifibrotic protective effect[1][2]
Molecular Weight:
588.44
Purity:
99.49
Formula:
C25H29IN6O3
Target:
AMPK
Application Notes:
Reference compound
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