FTO-IN-10 (compound 7) is a potent human demethylase FTO (the fat mass and obesity-associated protein) inhibitor with an IC50 of 4.5 µM. FTO-IN-10 enters the FTOs structural domain II binding pocket through hydrophobic and hydrogen bonding interactions.
Molecular Weight:
388.42
Formula:
C22H20N4O3
Target:
Autophagy,Fat Mass and Obesity-associated Protein (FTO)
Application Notes:
Reference compound
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