KY386 is a potent, selective inhibitor of DHX33 helicase, with the IC50 of 19 nM. KY386 inhibits U251-MG cells (DHX33-overexpressing cancer cell strain) with IC50 of 20 nM.and shows potent anti-cancer activity and moderate metabolic stability[1].
Molecular Weight:
405.47
Purity:
99.01
CAS Number:
[2787598-01-8]
Formula:
C21H19N5O2S
Target:
DNA/RNA Synthesis
Application Notes:
Reference compound
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