GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 µM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-alpha production in human primary macrophages with an IC50 of 9 µ
Molecular Weight:
453.96
Purity:
98.83
CAS Number:
[1797983-09-5]
Formula:
C24H28ClN5O2
Target:
Histone Demethylase
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted