Poziotinib (HM781-36B) is an orally active, irreversible pan-HER inhibitor, which effectively inhibits EGFRwt, HER-2 and HER-4 with IC50s of 3.2, 5.3 and 23.5 nM, respectively. Poziotinib (HM781-36B) also shows excellent inhibitory activities against mut
Molecular Weight:
491.34
Purity:
99.96
CAS Number:
[1092364-38-9]
Formula:
C23H21Cl2FN4O3
Target:
Apoptosis,EGFR
Application Notes:
Reference compound
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