AKE-72 (compound 5) is a potent inhibitor of Pan-BCR-ABL. AKE-72 inhibits BCR-ABLWT, BCR-ABLT315, BCR-ABLE255K, BCR-ABLF3171, BCR-ABLH396P and BCR-ABLQ252H with IC50s of [1].
Molecular Weight:
546.59
Purity:
98.29
CAS Number:
[2566525-18-4]
Formula:
C30H29F3N6O
Target:
Bcr-Abl
Application Notes:
Reference compound
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