AGI-6780 that potently and selectively inhibits the tumor-associated mutant IDH2R140Q with IC50 of 231.7 nM. AGI-6780 is less potent against IDH2WT with IC50 of 1908.1 nM.
Molecular Weight:
481.51
Purity:
98.87
CAS Number:
[1432660-47-3]
Formula:
C21H18F3N3O3S2
Target:
Isocitrate Dehydrogenase (IDH)
Application Notes:
Reference compound
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