BET-IN-21 (compound 16) is a blood-brain barrier-permeable extra terminal domain (BET) inhibitor with the Ki of 230 nM. BET-IN-21 inhibits microglia activation and has ameliorative effects on experimental autoimmune encephalomyelitis mice[1].
Molecular Weight:
344.41
CAS Number:
[3014815-06-3]
Formula:
C20H20N6
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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