GLPG3312 (Compound 28) is a selective pan-SIK inhibitor with IC50 values of 2.0 nM, 0.7 nM and 0.6 nM for SIK1, SIK2 and SIK3, respectively. GLPG3312 exhibits anti-inflammatory and immunomodulatory activity in vitro on human primary myeloid cells and in
Molecular Weight:
453.44
Purity:
98.25
CAS Number:
[2340388-72-7]
Formula:
C23H21F2N5O3
Target:
Salt-inducible Kinase (SIK)
Application Notes:
Reference compound
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