PSI-7409 tetrasodium is an active 5-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 µM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
Molecular Weight:
588.09
Purity:
99.31
CAS Number:
[1621884-22-7]
Formula:
C10H12FN2Na4O14P3
Target:
HCV
Application Notes:
Reference compound
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